A General Mechanism for Tuning: Gain Control Circuits and Synapses Underlie Tuning of Cortical Neurons
نویسندگان
چکیده
Tuning to an optimal stimulus is a widespread property of neurons in cortex. We propose that such tuning is a consequence of normalization or gain control circuits. We also present a biologically plausible neural circuitry of tuning. Copyright c © Massachusetts Institute of Technology, 2004 This report describes research done at the Center for Biological & Computational Learning, which is in the McGovern Institute for Brain Research at MIT, as well as in the Dept. of Brain & Cognitive Sciences, and which is affiliated with the Computer Sciences & Artificial Intelligence Laboratory (CSAIL). This research was sponsored by grants from: Office of Naval Research (DARPA) Contract No. MDA972-04-1-0037, Office of Naval Research (DARPA) Contract No. N00014-02-1-0915, National Science Foundation (ITR/IM) Contract No. IIS-0085836, National Science Foundation (ITR/SYS) Contract No. IIS-0112991, National Science Foundation (ITR) Contract No. IIS-0209289, National Science Foundation-NIH (CRCNS) Contract No. EIA-0218693, National Science Foundation-NIH (CRCNS) Contract No. EIA-0218506, and National Institutes of Health (Conte) Contract No. 1 P20 MH66239-01A1. Additional support was provided by: Central Research Institute of Electric Power Industry, Center for e-Business (MIT), Daimler-Chrysler AG, Compaq/Digital Equipment Corporation, Eastman Kodak Company, Honda R&D Co., Ltd., ITRI, Komatsu Ltd., EugeneMcDermott Foundation, Merrill-Lynch,Mitsubishi Corporation, NEC Fund, Nippon Telegraph& Telephone, Oxygen, Siemens Corporate Research, Inc., Sony MOU, Sumitomo Metal Industries, Toyota Motor Corporation, and WatchVision Co., Ltd.
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